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Hydroxycitric Acid

Time:2014-03-13 15:29:27   Hite:542

Name: Hydroxycitric Acid

Source: Garcinia cambogia extract


Molecular Structure:


Molecular Formula:C6H8O8

Molecular Weight: 208.12

Effects: Hydroxycitric acid (HCA) is a derivative of citric acid that is found in a variety of tropical plants including Garcinia cambogia and Hibiscus subdariffa. Laboratory and animal studies of HCA have produced results that indicate a potential for modulation of lipid metabolism;consequently HCA is an ingredient in some weight loss products and dietary supplements. However, clinical study has demonstrated that HCA has no effect in terms of weight loss or reduction of fat mass.
One isomer of HCA, known as (2S,3R)-HCA, inhibits pancreatic alpha-amylase and intestinal alpha-glucosidase, leading to a reduction in carbohydrate metabolism in vitro. In a study in Zucker rats which are genetically predisposed to obesity, Garcinia cambogia extract containing HCA showed that high doses led to significant suppression of epididymal fat accumulation, but also caused potent testicular atrophy and toxicity


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